Types of Cancer

Myelofibrosis is a chronic and progressive bone marrow disorder characterized by the replacement of bone marrow with fibrous scar tissue. This disruption affects the body’s ability to adequately produce blood cells.

Most people with myelofibrosis have a mutation or abnormal change in their DNA related to the disease. In particular, mutations in the JAK2, CALR, and MPL genes have been linked to the disorder.

Common Symptoms:

  • Fever
  • Weight loss
  • Night sweats
  • Extreme fatigue
  • Bone or joint pain
  • Shortness of breath
  • Easy bruising or bleeding
  • Sensation of pain or fullness below ribs on left side

We have blog topics delving into myelofibrosis - such as what it is, its symptoms, how it is treated, and advice for living with the disorder. You can find them below.


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